Thank you for the log file. I'm seeing problems with Photo Mechanic being unable to open it's own temp files. It appears as though some other app is interfering.
Are you running any Antivirus applications other than Windows Defender? If so, does the issue persist if you disable your AV apps?
Do you have any apps other than Photo Mechanic browsing these folders? I recommend closing all other applications to see if that resolves the issue.
HTH,
Jerry