I don't know the product you mentioned so I can't comment on it. But to answer your original question, here's my approach.
1. On my Mac I use the OS built in Time Machine to make automatic and regular (hourly) and "versioned" backups of my complete system (excluding some rapidly changing files as well as virtual machine images).
2. The files I excluded in step 1 (and which I find important), I backup manually using a command-line script I wrote myself. This script is built around the command-line tool rsync, and does make versioned backups as well (each version includes all files, but only the changed files take up space).
3. Step 1 and 2 backup to a constantly attached external HD. For extra safety I also create a backup of all my user files to two sets of backup disks. These sets get rotated, with one copy always stored externally. This way when my house burns down or things get stolen, I at least have a backup of my files. This backup is not versioned, and is created using rsync as well.
As you are on a PC, I suggest you look for something similar to perform step 1 with. Perhaps the software you mentioned does this.
Step 2 can be done perfectly well on the PC as well (rsync is available); heck the (now perl) script I use, I originally wrote and used on a PC!
Step 3 can easily be performed with synctoy (or by rsync) on the PC.
Cheers,
Hayo