Without having PM6 running first? It depends on whether your PM6 starts up when a card is inserted. Does yours? What OS do you run Photo Mechanic 6 on? The instructions are different for macOS than Windows.
Without configuring PM6 to start up when a card is inserted, you can still auto-ingest by manually starting up PM6 and leave it running in the background.
Start PM6. Open the Ingest dialog and get it set up with your desired options. Set the "Auto Ingest" checkbox. Click the "Close" button.
When you insert a camera card into your card reader, the Ingest will start a few moments later.
-Kirk